Products : Cellulose Acetate Phthalate
We provide enteric coating agents and excipients like
- Cellulose Acetate Phthalate (C.A.P.) which also plays a pivotal role in gastric fluid resistant coating, sustained release, matrix binder and taste masking for tablets, capsules and pellets is regarded as a non-toxic material free from any adverse effect.
- Hydroxy Propyl Methyl Cellulose Phthalate also known as Hypromellose Phthalate or HPMC Phthalate. Hypromellose Phthalate is widely used in oral pharmaceuticals formulations viz..tablets, capsules, pellets, as an enteric coating material, sustained release formulations, matrix former and for taste masking.
C.A.P. as well as Hypromellose Phthalate can be used along with the other excipients like colours, glidants to achieve targeted coating.
Cellulose Acetate Phthalate is our product of repute.
Synonyms: C.A.P. or Cellacefate or Cellacephate or Cellulose Acetate1,2-benzene Dicarboxylate.
CAS No.: 9004-38-0.
Structure:
Specification:
| Test | BP | USP/NF | EP | IP |
| Description | Complies | Complies | Complies | Complies |
| Solubility | Complies | Complies | Complies | Complies |
| Appearance of film | Complies | Complies | Complies | Complies |
| Identification | Comply | Comply | Comply | Comply |
| Viscosity @25° C | 45mPas-90mPas | 45cps-90cps | 45mPas-90mPas | 50mm2 s-1 to 90mm2 s-1 |
| Free Acid | Max. 3.0 % | Max. 3.0 % | Max. 3.0 % | Max. 3.0 % |
| Residue on Ignition | Max. 0.1% | |||
| Sulphated Ash | NMT 0.1 % | Max. 0.1 % | Max. 0.1 % | |
| Water Content | Max. 5.0 % | Max. 5.0 % | Max. 5.0 % | Max. 5.0 % |
| Phthalyl content | 30.0%-36.0% | 30.0%-36.0% | 30.0%-36.0% | 30.0%-40.0% |
| Acetyl content | 21.5% - 26.0% | 21.5% - 26.0% | 21.5% - 26.0% | 17.0% - 26.0% |
| Heavy Metals | NMT 10ppm | NMT 0.001% | Max. 10ppm | NMT 20ppm |
| OVI | Meets Requirement |
Physical Form:
Powder, granules/flakes
Properties:
C.A.P. resists gastric fluid of stomach but readily dissolves in enteric fluid of small intestine.
C.A.P. is available in following standard specification: BP/USP/NF/EP/IP
It can also be made and supplied as per other recognised pharmacopeia.
Application:
- Film coating of tablets, pellets and capsules
- Enteric coating of tablets, pellets and capsules
- Sustained release formulations
- Delayed release formulations
- Pellet Coating
- Taste masking
Advantages of film coating:
- Sootherns pelletability by masking unpleasant taste or odor of the medicaments
- Eases swallowing
- Enhances product appearance
- Protection of formulation from air oxidation, moisture and light
- Improves the efficacy of drug.